Image sharpness and noise reduction can be controlled in the Details Tool Tab. It includes Advanced Noise Reduction, Moiré, and Dust/Spot removal tools.
The Details Tool Tab includes combined navigation and the focus tool that allows users to quickly inspect detail close-up anywhere on the image at any zoom level. The Focus window can be used to keep track of the sharpness at a 100% view.
Note that the Layers tool near the top allows you to make localized adjustments with masks. This tool is also available in some other Tabs.